Plasticizer (packaging/processing migrant)
Also known as: DEHP, Bis(2-ethylhexyl) phthalate, DOP, CAS 117-81-7, EC 204-211-0
High-volume phthalate plasticizer that migrates into food from plastic food-contact materials and processing equipment. Regulated in the EU as a REACH Substance of Very High Concern (toxic for reproduction / endocrine disruptor), covered by an EFSA group TDI for phthalates, and listed under California Prop 65 as a developmental and male reproductive toxicant and a carcinogen.
Bis(2-ethylhexyl) phthalate (DEHP) is classified as toxic for reproduction (category 1B) and is included in Annex XIV - the REACH Authorisation List - of Regulation (EC) No 1907/2006 pursuant to Article 57(c), by Commission Regulation (EU) No 143/2011.
DEHP is classified as toxic for reproduction (category 1B) and is on the REACH Authorisation List (Annex XIV) under Article 57(c), per Commission Regulation (EU) No 143/2011.
DEHP is listed by California (Proposition 65) as known to the state to cause cancer (since 1988) and as causing developmental toxicity and male reproductive toxicity (since 2003).
California (Proposition 65) lists DEHP as known to cause cancer (since 1988) and as causing developmental and male reproductive toxicity (since 2003).
EFSA set a temporary group tolerable daily intake (TDI) of 50 ug/kg bw/day for DBP, BBP, DEHP and DINP, based on their shared effect of reducing fetal testosterone, for use in food contact materials.
EFSA set a temporary group tolerable daily intake of 50 ug/kg bw/day for DBP, BBP, DEHP and DINP in food-contact materials, based on their shared reduction of fetal testosterone.
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